Course Description

410.639 - Protein Bioinformatics

Because the gap between the number of protein sequences the number of protein crystal structures continues to expand protein structural predictions are increasingly important. This course provides a working knowledge of various computer- based tools available for predicting the structure and function of proteins. Topics include protein database searching, protein physicochemical properties, secondary structure prediction, a statistical verification. Also covered are graphic visualization the different types of three-dimensional folds and predicting 3-D structures by homology. Computer laboratories complement material presented in lectures. Prerequisites: 410.601 Biochemistry, 410.602 Molecular Biology, 410.633 Introduction to Bioinformatics. S