Student and Alumni Bibliography

Armando Salim Muñoz Abraham

Armando Salim Munoz
What was your background before coming to Johns Hopkins? Did you complete the program as a full-time or part-time student? 
I was born and raised in Mexico. After obtaining my medical degree at the Universidad Anahuac medical school in Mexico City, I applied for the Master’s Degree at Johns Hopkins with the idea to have a background in Biotechnology and all that it entails before pursing further specialization in surgery.

I completed the MBEE as a full-time student since I was planning to apply my master’s knowledge in a University setting doing research and then apply for surgery residency.

What were your career objectives and have they changed since pursuing your MBEE? Before the master’s degree I intended to apply to neurosurgery residency. However, after completing the MBEE, I found a position as a postdoctoral research associate in Transplant Surgery at the Yale University school of Medicine. There I was able to do basic and clinical research, and developed new technologies in collaboration with the Yale School of Engineering. We also collaborated with the Yale School of Business with the idea to establish a startup company in order to bring one of our technologies to the market. Within one year of research at Yale, I was able to apply all the knowledge from my master’s degree since I was working with new technologies, tech transfer, developing business plans, applying for grants, among other things. At that time, I realized how passionate I was toward transplant surgery and the potential for innovation in the field. Now my career objective is to become a pediatric transplant surgeon that can bring innovation in many areas of the field to help address unmet needs in transplant bringing together the skills of a surgeon along with the skills from my master’s degree.

Why did you decide to pursue your MBEE? The field of surgery requires continuous innovation. The new ideas require extensive knowledge not only in science but what it takes to bring that idea to the patient, and that alone entails knowledge in patents and law, regulatory affairs, marketing, business, tech transfer, and industry. I wanted to have the mindset and skills that are required to understand the field of biotechnology in its entirely before further specializing, so that as a young physician scientist I could start developing my own technologies directed to unmet needs in my field, and become an entrepreneur that can bring significant changes to medicine.

How do you use your MBEE in your everyday work life? It definitely created a major change in my life and career. I can tell that my mindset definitely changed with what I learned and applied during the masters. The way I approach projects and seek opportunities is different to what we physician are usually trained for. Now, I understand better that what is important is to look at the big picture and always tailor your efforts towards technologies or discoveries that can create a change and impact the world, instead of focusing on what one personally believes is the best. Also, now I understand the resources and multidisciplinary effort that are required to develop a technology. I try to get involved in projects that allow collaboration between different disciplines since this is the key for ideas to become a real successful product.

Would you do anything differently from your time at Hopkins? I think overall it was a great experience. The program offers a wide variety of courses that allows the student to tailor their masters according to their field of work or study. This has definitely promoted skill formation. Looking back at my time with Johns Hopkins, I don’t think I would have done anything differently.

Are there any aspects from the program that stuck out to you as particularly helpful in relation to your success? Yes, particularly tech transfer. I believe it is very important for scientist to understand that research needs to be focused on addressing unmet needs and looking out there to figure out what the market is looking for. Now I try to look for opportunities for development were other people are not looking at or things that really impact the health of the population. I touch this last point because the social entrepreneurship course also impacted my thinking and training in many ways. Following the example of visionary people that have created impact in health in underdeveloped areas by establishing enterprises with the commitment to help the people by involving the community is something that really attracts me and eventually I want to become a social entrepreneur, an agent of change.

What do you see yourself doing after your pediatric surgery research? I will continue my training as a general surgeon, to eventually become a pediatric transplant surgeon working in an academic center doing both surgeries and research. Along with this, I want to become a social entrepreneur and create technologies that can be brought to the developing world to aid the poor in countries such as my beloved Mexico.

Did you have a favorite course or professor? In particular, I really liked the tech transfer, finance in biotechnology and social entrepreneurship courses.

The majority of the MBEE program is online, how did that affect your experience with the program? It didn´t really affect my experience. I think I got the best from both worlds (onsite and online). The program is flexible in that way.

What was your experience like as an international student? My experience was unique. The program director, coordinators and staff were always very helpful and they really are great mentors. They are devoted to give advice not only related to the masters but also related to the future of your career, as well as to facilitate your life in the United States. I was able to make a lot of friends as well since there are people from all around the country and the world doing this master’s degree. Now I have friends and former classmates all across the US and the world and we are still in communication, and I am sure that in the long run I will establish projects with them.

What is your advice to current or prospective MBEE students? My advice to future student would be to take advantage of the flexibility and wide variety of courses, the expertise of the professors and the available opportunities to develop your career. Johns Hopkins is always looking for getting the best training for their students and the master’s degree will give you the tools and skills to further succeed in your career in the field of Biotechnology.

The MBEE is a great program for physicians, scientist, lawyers, marketing experts and many others interested in developing a career in biotechnology.

David J. Auerbach

David J. Auerbach is a Consultant in the Life Sciences Strategy & Transformation practice at Capgemini Consulting in New York City. David’s background includes over 5 years of government and industry early stage research through clinical phase drug development (generic and innovative), as well as life science strategy consulting. From a business perspective, he has experience in commercial organizational design (including new product planning function design), product launch execution, strategic planning, in-licensing due diligence (target screening and prioritization), project management, and market research (including in-depth analyses using a variety of business and pharma-specific databases). From a scientific perspective, he has experience in clinical assay development, Laboratory Information Management Systems (LIMS) sample management, and bench biomedical research, where he studied HIV-related cytokines and cytokine receptors using various immunological techniques. After attending Cornell University (B.A. in Chemistry), he completed his M.B.A. and M.S. in Biotechnology dual degree from Johns Hopkins University. In 2012, he published his first scholarly scientific article. Read about it here:

  • David J. Auerbach, Yin Lina, Huiyi Miaoa, Raffaello Cimbroa, Michelle J. DiFiorea, Monica E. Gianolinia, Lucinda Furcib, Priscilla Biswasb, Anthony S. Faucia, and Paolo Lussoa: “Identification of the platelet-derived chemokine CXCL4/PF-4 as a broad-spectrum HIV-1 inhibitor” PNAS. View.

Karen Burce

Karen Burce works full-time as a senior clinical research coordinator for the Department of Surgery and the Department of Plastic and Reconstructive Surgery at Johns Hopkins School of Medicine. She has been working here for over a year. Previously, she earned a Master of Health Science in Molecular Microbiology and Immunology from the Johns Hopkins Bloomberg School of Public Health.

  • Kevin C. Soares, M.D., Pablo A. Baltodano, M.D., Caitlin W. Hicks, M.D., Carisa M. Cooney, M.P.H., Israel O. Olorundare, M.B.B.S., M.P.H., Peter Cornell, M.S.N., Karen Burce, M.H.S., Frederic E. Eckhauser, M.D., F.A.C.S. “Novel wound management system reduces surgical site morbidity after ventral hernia repairs: a critical analysis” The American Journal of Surgery, 2014. Download (PDF).

Moray Campbell

Dr. Moray Campbell is an Associate Professor at Rowell Park Cancer Institute (RPCI), USA. His research interests are focused around cancer epigenomics from a translational perspective with the aim to combine insight from a cell line, tumor models and patient material to understand disease risk and novel therapies. A central component of his research is based on leveraging publicly available data, and he has started the long journey of being able to conceive, design and interpret experiments both in Eppendorfs and at the command line. He is also an Associate Dean at RPCI and has a strong interest in designing innovative and interdisciplinary graduate-level training programs, both at the Ph.D. and M.S. level. For example, he established a program entitled CanSys, through the European Union-United States Atlantis Program, which fuses RPCI with two EU universities (The University of Luxembourg and the Free University, Amsterdam). The CanSys program develops quantitative modeling skills in MS students through taught courses and research undertaken at each of the three-member institutes. He is also leading the development of graduate curricula at RPCI.

Lei-Ann Chang

Lei-Ann Chang is a research technician for the FlyEM Project. Specifically, her job is an EM proofreader. Before joining HHMI, Lei-Ann was a medical assistant. Lei-Ann’s daily routines included studying MRI, CT, and X-ray images. Lei-Ann has four AS degrees (Business Administration, Computer Science, Information Systems, and Mathematics), BS in IT Network Security from George Mason University, post-baccalaureate Pre-Med Certificate from Georgetown University and she am currently working on my MS in Biotechnology/Bioinformatics from The Johns Hopkins University. During her free time, Lei-Ann enjoys playing with her two kids and three very fuzzy dogs.

  • Shin-ya Takemura, Arjun Bharioke, Zhiyuan Lu, Aljoscha Nern, Shiv Vitaladevuni, Patricia K. Rivlin, William T. Katz, Donald J. Olbris, Stephen M. Plaza, Philip Winston, Ting Zhao, Jane Anne Horne, Richard D. Fetter, Satoko Takemura, Katerina Blazek, Lei-Ann Chang, Omotara Ogundeyi, Mathew A. Saunders, Victor Shapiro, Christopher Sigmund, Gerald M. Rubin, Louis K. Scheffer, Ian A. Meinertzhagen & Dmitri B. Chklovskii: “A visual motion detection circuit suggested by Drosophila connectomics” Nature 500 published August 2013. View.

Kathryn Cole

Kathryn Cole, a native of Sullivan’s Island, SC, received her BS in Neuroscience at Davidson College in Davidson, NC, where her research focused on psychopharmacology and drugs of abuse. Following graduation, Kathryn entered the field of consulting on pioneering healthcare products in the DC metro area. She received her Masters in Biotechnology Enterprise and Entrepreneurship from Johns Hopkins University while continuing to work full-time, and is presently a Senior Consultant in the Translational and Regulatory Sciences practice at Precision for Medicine, which was established to provide value-added scientific and regulatory solutions for development, marketing authorization, regulatory compliance, and stewardship of innovative healthcare products.

  • Kathryn Cole and Merry Lee Bain: “Post-market device surveillance in the US: the MedWatcher platform.” SCRIP Regulatory Affairs published in 2013. Download (PDF).

Mahesh Datla

As an undergraduate, Mahesh Datla attended Virginia Commonwealth University majoring in Biomedical Engineering. After graduating, Mahesh worked at the National Institutes of Standards and Technology. He then applied to the MS/MBA program in Biotechnology at Johns Hopkins. On top of all his business and biotechnology requirements, Mahesh took the one-year-long Masters thesis course. For his Masters thesis, Mahesh worked at the National Cancer Institute at the Cancer Inflammation Program under the guidance of Dr. Yinling Hu. Mahesh graduated from Johns Hopkins with an MS/MBA in Biotechnology in December 2012. Read about his recent publication here:

  • Zuoxiang Xiao, Qun Jiang, Jami Willette-Brown, Sichuan Xi, Feng Zhu, Sandra Burkett, Timothy Back, Na-Young Song, Mahesh Datla, Zhonghe Sun, Romina Goldszmid, Fanching Lin, Travis Cohoon, Kristen Pike, Xiaolin Wu, David S. Schrump, Kwok-Kin Wong, Howard A. Young, Giorgio Trinchieri, Robert H. Wiltrout and Yinling Hu: “The Pivotal Role of IKKa in the Development of Spontaneous Lung Squamous Cell Carcinomas,” Cell Press, April 2013. View.

Johanna Dennis

Johanna Dennis joined the faculty at Southern Illinois University in 2013, where she teaches Torts and Lawyering Skills I. She was previously a member of the law faculties at Southern University in Baton Rouge, Vermont Law School, Touro College – Jacob D. Fuchsberg Law Center, and Florida A and M University College of Law, where she taught classes in Patent law, Intellectual Property law, Immigration law, Commercial Papers, Federal Courts, Law and Medicine: Bioethics, and Legal Research and Writing. Prior to joining the legal academy, Professor Dennis clerked for the Honorable William P. Gilroy (ret.) in the Superior Court of New Jersey, Appellate Division, and she worked on civil service employment appeals with the State of New Jersey, Department of Personnel, Division of Merit System Practices and Labor Relations. Professor Dennis has practiced immigration law and researches in immigration law and patent law. She also serves as a Deputy Editor for the American Bar Association’s Section of International Law – International Law News, and as Editor-in-chief for the International Journal of Liability and Scientific Enquiry. Professor Dennis holds a J.D. from Temple University, a B.A. from Rutgers University, an M.S. in Biotechnology from The Johns Hopkins University, and an M.A.Ed. in Higher Education from Trident University. She is admitted to the Pennsylvania Bar, the U.S. Court of Appeals for the Second Circuit, and the U.S. Patent and Trademark Office.

  • Dennis, Johanna K.P. “What’s mine is mine and what’s yours is mine too: Converging U.S. intellectual property exhaustion doctrines.” Computer Law & Security Review 30:1 published in 2014. View.
  • Dennis, Johanna K.P. “Owning Methods of Conducting Business in Cyberspace” Cyberspace Law Ed. Hannibal Travis. Routledge, 2013. View.

Sean Evans

Sean L. Evans received his undergraduate degree in Biology from the College of Charleston in Charleston, South Carolina. During his undergraduate years, Sean participated in multiple summer research programs, including the Duke University Summer Research Opportunities Program and the Ronald E. McNair Scholars Program. After graduation, Sean volunteered as a Biology and Mathematics Education Volunteer with the United States Peace Corps in Tanzania (East Africa) for two years. Upon returning to the United States, he was selected to participate in the Post-Baccalaureate Research Education Program (PREP) at Johns Hopkins University. While a PREP scholar, Sean researched the effects of mercury on the immune system as well as completed a graduate degree in Biotechnology (MS). Prior to entering his doctoral program, Sean also participated in a summer research program at the National Institutes of Health. Sean is currently in his fifth year of doctoral research in the area of HIV-host protein interactions. His doctoral thesis has focused on the assembly of a viral E3 ubiquitin ligase complex including HIV-1 accessory protein, viral infectivity factor (Vif) and host factors that are required for Vif function and HIV survival. His work has further characterized how all of these proteins come together using in vitro and in vivo cell-based assays. Sean has co-authored eleven peer-reviewed publications and was a recipient of the Ruth L. Kirschtein National Research Service Award Pre-doctoral Fellowship. In addition to his doctoral research, Sean was an analyst intern with the Johns Hopkins Office of Technology Transfer until November 2013. In this capacity, he reviewed new technologies from multiple fields, including the life and physical sciences as well as medical devices and software applications. Furthermore, he performed prior art, patentability, as well as market analyses in order to generate a technical report and marketing summary for each invention. Sean will defend his dissertation on February 10, 2014, and pursue a career in life sciences research and/or consulting at a biotechnology/pharmaceutical company, a government research agency, or a private firm.

Waleed Haso

Waleed Haso earned his bachelor of science in Bioinformatics from Ramapo College of New Jersey in 2010 magna cum laude. As an undergraduate, Waleed was involved in Bioinformatics research through interning at the Boyce Thompson Institute for plant research at Cornell University working on developing web tools and databases for the international tomato genome project. In 2010, Waleed was awarded the NCI/JHU fellowship in molecular targets and drug discovery. He worked in the pediatric oncology branch under directions of Dr. Crystal Mackall and Dr. Rimas Orentas on engineering T cells with chimeric antigen receptors for the immunotherapy of B cell malignancies targeting CD22. Waleed earned his M.S. In Biotechnology in 2012 and published his paper in Blood. Currently, he remains in the pediatric oncology branch to work under directions of Dr. Terry Fry performing preclinical experiments of the anti-CD22 Chimeric antigen receptor to plan for clinical trials. His future plan is to attend medical school and practice pediatrics. Read about his recent publication here:

  • Waleed Haso, Damiel W. Lee, Nirali N. Shah, Maryalice Stetler-Stevenson, Constance M. Yuan, Ira H. Pastan, Dimiter S. Dimitrov, Richard A. Morgan, David J. FitzGerald, David M. Barrett, Alan S. Wayne, Crystal L. Mackall, and Rimas J. Orentas: “Anti-CD22-chimeric antigen receptors targeting B cell precursor acute lymphoblastic leukemia.” Blood Journal, published in December 2012. View Online.

Ross Haynes

Ross Haynes started working at NIST in August 2005 after graduating from James Madison University Magna Cum Laude. He has since completed a master’s degree in Biotechnology at Johns Hopkins University. He is part of the Applied Genetics Group in the Biomolecular Measurement Division and is currently working on DNA-based reference materials of clinical relevance.

  • Jim F. Huggett, Carole A. Foy, Vladimir Benes, Kerry Emslie, Jeremy A. Garson, Ross Haynes, Jan Hellemans, Mikael Kubista, Reinhold D. Mueller, Tania Nolan, Michael W. Pfaffl, Gregory L. Shipley, Jo Vandesompele, Carl T. Wittwer, and Stephen A. Bustin: “The Digital MIQE Guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments” Clinical Chemistry 59:6 published in 2013. Download (PDF).

Jason T. Howard

Jason Howard is a Research Specialist for HHMI at Duke University. He is currently working as the program coordinator for the B10K project. The goal of the B10K project is to sequence the genomes of all 10,000 species of birds. Jason is working with the University of Copenhagen, BGI, and the Smithsonian to collect the samples for genome sequencing. He uses the genome sequence data along with gene expression data to map areas of the brain involved in vocal learning. The gene expression data in songbirds is being compared to gene expression data produced by the Allan Brain Institute to more precisely map the areas of the human brain involved in speech. Jason Howard received his BS from Florida State University and his MS from the University of North Carolina at Chapel Hill. Before working at Duke University, he worked at Cogent Neuroscience looking for developing assays to screen for compounds to be used to fight Huntington’s disease and Alzheimer’s disease.

  • Six Publications in Science Mag, December 2014
  • Osceola Whitney, Andreas R. Pfenning, Jason T. Howard, Charles A Blatti, Fang Liu, James M.Ward, Rui Wang, Jean-Nicolas Audet, Manolis Kellis, Sayan Mukherjee, Saurabh Sinha, Alexander J. Hartemink, Anne E. West, Erich D. Jarvis “Core and region enriched networks of behaviorally regulated genes and the singing genome.” Science, 2014.
  • Andreas R. Pfenning, Erina Hara, Osceola Whitney, Miriam V. Rivas, Rui Wang, Petra L. Roulhac, Jason T. Howard, Morgan Wirthlin, Peter V. Lovell, Ganeshkumar Ganapathy, Jacquelyn Mouncastle, “Convergent transcriptional specializations in the brains of humans and song learning birds.” Science, 2014.
  • Ganapathy G, Howard J.T, Ward JM, Li J, Li B, Li Y, Xiong Y, Zhang Y, Zhou S, Schwartz DC, Schatz M, Aboukhalil R, Fedrigo O, Bukovnik L, Wang T, Wray G, Rasolonjatovo I, Winer R, Knight JR, Koren S, Warren WC, Zhang G, Phillippy AM, Jarvis ED. “High-coverage sequencing and annotated assemblies of the budgerigar genome.” Gigascience, 2014 Jul 8;3:11. doi: 10.1186/2047-217X-3-11. Guojie Zhang et. al. “Comparative Genomics Reveals Insights into Avian Genome Evolution and Adaptation.” Science, 2014.
  • Erich D. Jarvis, Siavash Mirarab, Andre J. Aberer, Bo Li, Peter Houde, Cai Li, Simon Y. W. Ho, Brant C. Faircloth, Benoit Nabholz, Jason T. Howard, Alexander Suh, Claudia C. Weber et. al “Whole Genome Analyses Resolve the Early Branches to the Tree of Life of Modern Birds.” Science, 2014. Richard E Green, et. al. “Three crocodilians genomes reveal ancestral patterns of evolution among archosaurs.” Science, 2014.
  • Rui Wang, Chun-Chun Chen, Erina Hara, Miriam V. Rivas, Petra L. Roulhac, Jason T. Howard, Mukta Chakraborty, Jean-Nicolas Audet, and Erich D. Jarvis “Convergent differential regulation of SLIT-ROBO axon guidance genes in the brains of vocal learners.” Comparative Neurology Science, 2014.
  • Erich D. Jarvis, Siavash Mirarab, Andre J. Aberer, Bo Li, Peter Houde, Cai Li, Simon Y. W. Ho, Brant C. Faircloth, Benoit Nabholz, Jason T. Howard, Alexander Suh, Claudia C. Weber, Rute R. da Fonseca, Alonzo Alfaro-Núñez, Nitish Narula, Liang Liu, Dave Burt, Hans Ellegren, Scott V. Edwards, Alexandros Stamatakis, David P. Mindell, Joel Cracraft, Edward L. Braun, Tandy Warnow, Wang Jun, M Thomas P Gilbert, Guojie Zhang. “Phylogenomic Analyses Data of the Avian Phylogenomics Project” Gigascience, 2014.
  • Keith R Bradnam, et. al. “Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species” Gigascience, 2013. Download (PDF).
  • Ganeshkumar Ganapathy, Jason T Howard, James M Ward, Jianwen Li, Bo Li, Yingrui Li, Yingqi Xiong, Yong Zhang, Shiguo Zhou, David C Schwartz, Michael Schatz, Robert Aboukhalil, Olivier Fedrigo, Lisa Bukovnik, Ty Wang, Greg Wray, Isabelle Rasolonjatovo, Roger Winer, James R Knight, Sergey Koren, Wesley C Warren, Guojie Zhang, Adam M Phillippy, and Erich D Jarvis “High-coverage sequencing and annotated assemblies of the budgerigar genome” Gigascience, 2014. Download (PDF).
  • Erich D. Jarvis, Jing Yu, Miriam V. Rivas, Haruhito Horita, Gesa Feenders, Osceola Whitney, Syrus C. Jarvis, Electra R. Jarvis, Lubica Kubikova, Ana E.P. Puck, Connie Siang-Bakshi, Suzanne Martin, Michael McElroy, Erina Hara, Jason Howard, Andreas Pfenning, Henrik Mouritsen, Chun-Chun Chen, and Kazuhiro Wada “Global View of the Functional Molecular Organization of the Avian Cerebrum: Mirror Images and Functional Columns” The Journal of Comparative Neurology, 2013. Download (PDF).
  • Ricardo Antonio Rossello, Chun-Chun Chen, Rui Dai, Jason T Howard, Ute Hochgeschwender, Erich D Jarvis “Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species” eLife, 2013.
  • Sergey Koren, Michael C Schatz, Brian P Walenz, Jeffrey Martin, Jason T Howard, Ganeshkumar Ganapathy, Zhong Wang, David A Rasko, W Richard McCombie, Erich D Jarvis & Adam M Phillippy “Hybrid error correction and de novo assembly of single-molecule sequencing reads” Nature Biotechnology, 2012. Download (PDF).
  • John A St John, et. al. “Sequencing three crocodilian genomes to illuminate the evolution of archosaurs and amniotes” Genome Biology, 2012. Download (PDF).

Ginny Kwan

Ginny Kwan

Ginny Kwan is a graduate student in the Regulatory Science program at Johns Hopkins University. She is currently in her last semester and is working on an independent research project on medical device software regulations, under the supervision of Professor Jonathan Helfgott, Acting Associate Director for Risk Science, FDA CDER (JHU alumna 2007, MSc. in Bioscience Regulatory Affairs). Ginny holds a BSc. in biochemistry. She has worked in the areas of regulatory operations in the generic drug industry and computer system validation for life sciences companies. She is also an active member of CAPRA – the Canadian Association of Professionals in Regulatory Affairs, serving on the Student Relations Committee. Ginny is passionate about regulatory affairs, driven by a personal goal to help deliver safe and effective medical products to those in need as quickly as possible. She is particularly interested in using technology to advance medical science. Ginny lives in Montreal, Canada and is a Regulatory Affairs Associate at Zimmer Computer Assisted Surgery (CAS).   Statement by Ms. Kwan: “While collecting information for my independent project in medical device software regulations (supervised by Jonathan Helfgott), I landed a new job! I connected with an RA director from Zimmer’s Computer Assisted Surgery division to discuss my project and to obtain his point of view on current regulations. Jonathan had prepared me well. We had previously discussed some of the challenges and trends in medical device software regulations and he had directed me to the relevant guidance documents. I was well prepared for the meeting and it didn’t go unnoticed. After the meeting, I was invited to submit my candidature for a position in his department. I am now in my second week at Zimmer, in my new job as a regulatory affairs associate.”

  • Ginny Kwan “Online Regulatory Affairs Training from the US: An Alternative for Canadian Regulatory Affairs Professionals” News of Course 84 published in 2013. Download (PDF).

Seth Luty

Seth Luty graduated from Quinnipiac University in 2010 with a BS in biology with a concentration in Anatomy and Comparative Physiology. While attending Quinnipiac Seth worked full time as an Emergency Room Technician at Yale New Haven Hospital, which made it easy for Seth to transition to the Department of Emergency Medicine at Yale University when he graduated. Seth worked in Emergency Medicine for three years as a Lead Research Associate on a grant funded by AHRQ to reduce the amount of ionizing radiation patients with renal colic receive from CT scans. During his time in Emergency Medicine Seth also became a Filemaker developer. Using these skills he created databases from scratch that house all patient-related study data for the Department of Emergency Medicine’s federally funded research, which totals more than 8 million dollars in grants per year. The databases he created are accessible via iPad’s and allow for live electronic data capture in the Emergency Room. Because of Seth’s success in Emergency Medicine, he has consulted for other departments in the Yale School of Medicine, including the departments of Otolaryngology Surgery and Endocrine Surgery; helping their study teams determine what type of data, services and databases will best suit their needs. Outside Yale University, Seth is the database manager for a collaborative project between Kiaser Permanente Santa Clara Medical Center in California and Wellington Regional Hospital in New Zealand. He also is a Usability and Functionality Consultant and is currently helping a small tech start-up, SherlockMD, in Los Angeles, CA get their first website and iOS app launched. Lastly, he helps Health Bridges International, a non-profit organization dedicated to improving people’s health in developing countries through sustainable methods, with the analysis of data they have collected in Peru to examine the effectiveness of their programs. Seth currently works for the Yale Center for Clinical Investigation as an OnCore Research Coordinator. Seth started the JHU Biotechnology program in the fall of 2013 and plans to concentrate his studies in bioinformatics. After graduating he hopes to use his degree to help bridge the gap between the clinical research world and the IT world. Seth is particularly interested in translational bioinformatics and using big data from the electronic medical record to perform disease phenotyping.

  • Moore, C., Daniels, B., Singh, D., Luty, S., Molinaro, A., & Gross, C. (2013). “Prevalence and Clinical Importance of Alternative Causes of Symptoms Using a Renal Colic Computed Tomography Protocol in Patients With Flank or Back Pain and Absence of Pyuria.” Academic Emergency Medicine, 20(5), 470-478. Download (PDF).
  • Herbst, M.K., Rosenberg, G., Daniels, B., Gross, C.P., Singh, D., Molinaro, A., Luty, S., Moore, C.L. (2014) “Effect of Provider Experience on Clinician-Performed Ultrasonography for Hydronephrosis in Patients With Suspected Renal Colic.” Annals of Emergency Medicine View.
  • Christopher L Moore, Scott Bomann, Brock Daniels, Seth Luty, Annette Molinaro, Dinesh Singh, Cary P Gross: “Derivation and validation of a clinical prediction rule for uncomplicated ureteral stone—the STONE score: retrospective and prospective observational cohort studies” BMJ published in 2014. Download (PDF).

Laura Minang

Laura Minang is currently working her MS in Biotechnology here at Hopkins. She is a native of Cameroon, West Africa, and received her Bachelor of Arts Degree in Biology at Johns Hopkins University. She is currently an R&D Laboratory Technician at Champions Oncology working on projects that involve the development and use of Patient-derived Xenograft (PDX) models in humanized mice to test immunotherapy approaches targeting immune checkpoints. Her future goal is to become a Physician.

Nipun A. Mistry

After graduating from Johns Hopkins with a master’s in Bioinformatics, Nipun A. Mistry joined Texas Medical Center as a bioinformatics/statistical analyst. Nipun is currently working on multiple next-generation sequencing data analysis and software development projects. Nipun also participates in protocol development and is a consultant to investigators in the institution. Nipun is interested in medical genomics, personalized medicine, big-data analysis, computational biology, and programming. Nipun is originally from Mumbai, India. Nipun grew up in Singapore and completed an undergraduate degree in engineering back in India. Nipun’s hobbies include reading, programming, cooking and learning new languages. Read about recent publications here:

  1. Christopher J. Donnelly, Ping-Wu Zhang, Jacqueline T. Pham, Aaron R. Heusler, Nipun A. Mistry, Svetlana Vidensky, Elizabeth L. Daley, Erin M. Poth, Benjamin Hoover, Daniel M. Fines, Nicholas Maragakis, Pentti J. Tienari, Leonard Petrucelli, Bryan J. Traynor, Jiou Wang, Frank Rigo, C. Frank Bennett, Seth Blackshaw, Rita Sattler, and Jeffrey D. Rothstein, “RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention,” Neuron 80, published October 2013. Download (PDF).
  2. Peter K. Todd and Henry L. Paulson, “C9orf72-Associated FTD/ALS: When Less Is More,” Neuron 80, published October 2013. Download (PDF).

Jarrett D. Morrow

In 2005, the threat of an avian influenza pandemic was the trigger for Jarrett Morrow to begin changing careers from engineering to the biological sciences. A solid educational foundation was achieved through on-ground coursework at local colleges, however having previously earned a Ph.D. in Electrical Engineering, it was apparent that graduate studies would be necessary to gain employment, and this proved to be difficult while continuing to work full time. The Master of Science in Biotechnology program in 2007 was a perfect option based on the reputation of The Johns Hopkins University and the online course structure. Fast forward to the end of 2008, when Jarrett and his wife brought their twin daughters home from China, the biotechnology program was nearing completion. After weighing several options in 2009, they concluded that being the caregiver for their daughters, while continuing graduate studies, was the correct plan for Jarrett; the Master of Science in Bioinformatics program was a natural extension of the biotechnology degree, as well as a complement to Jarrett’s engineering background. Although resigning from his engineering position in 2009 to enable this was extremely difficult, particularly considering the economic climate at the time, the ensuing process has proven to be extremely rewarding. Jarrett’s path has been fruitful, albeit non-traditional, and has been paved with challenging coursework and published research projects conducted with inspired and generous individuals. In particular, having taken two courses with Dr. Higgs, he graciously acted as Jarrett’s mentor on one of his research projects. He went above and beyond in these efforts and truly exemplified the spirit of Johns Hopkins University. In the summer of 2012, an internship opportunity at the Channing Division of Network Medicine at Brigham and Women’s Hospital provided full-time experience, as Jarrett’s graduation in December 2012 neared. Following the internship, Jarrett was fortunate enough to gain full-time employment as a Bioinformatics Programmer/Analyst, while at the same time earning the M.S. in Bioinformatics degree. His journey continues, and he will always be grateful for the opportunities that the Advanced Academic Programs provided. Read about his recent publication here:

  • Jarrett D. Morrow and Brandon W. Higgs: CallSim: Evaluation of Base Calls Using Sequencing Simulation, ISRN Bioinformatics, published 2012. View.

Christopher Nguyen

Christopher Nguyen is a Biotechnology graduate student and Research Assistant in the Department of Pathology at the Johns Hopkins School of Medicine. He obtained his Bachelor of Science degree in Molecular Biology and Biochemistry from Gettysburg College, Pennsylvania. Chris contributed to the work on an innovative dual fluorescent protein reporter, termed HypoxCR, which can simultaneously detect cells that are hypoxic and/or cycling to study the effects of the tumor’s microenvironment on the sensitivity to metabolic inhibitors which was published in Proceedings of the National Academy of Sciences of the United States of America in 2014 in which he is the second author. Chris also participated in the Department of Pathology Young Investigators’ Day in which he presented his work on the metabolic signature of resistant breast cancers to metabolic inhibitors in order to detect likely responders and non-responders to this emerging treatment.

  • Anne Lea, Zachary E. Stinec, Christopher Nguyen, Junaid Afzal, Peng Sun, Max Hamaker, Nicholas M. Siegel, Arvin M. Gouw, Byung-hak Kang, Shu-Han Yu, Rory L. Cochran, Kurt A. Sailor, Hongjun Song, and Chi V. Dang “Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia–cell cycle dual reporter” PNAS, 2014. Download (PDF).

Atara Noiade

Dr. Noiade practices Chinese Medicine including acupuncture on Bainbridge Island, WA and holds an M.BioSci from Johns Hopkins in Regulatory Affairs. She is an NCCAOM Diplomate in Herbal Medicine and has served as Chair of the Herbal Medicine Committee of the American Association of Acupuncture and Oriental Medicine. Read about Dr. Noiade’s recent publications here:

  • Atara Noiade, “The Impact of FDA Enforcement of DSHEA on the Practice of Traditional Asian Herbal Medicine,” Update magazine, published December 2012. Download (PDF).
  • Atara Noiade, “Drug Reimportation: Is It the Solution to the High Cost of Prescription Drugs in the US?” Regulatory Focus magazine, published April 2013. Download (PDF).
  • Atara Noiade, “DSHEA: Preserving Legal Access to Chinese Medicine or Researching New Remedies for Malaria and Other Tropical Diseases” Regulatory Focus magazine, published July 2015.

Houtan Noushmehr

Houtan Noushmehr’s academic training and research experience have provided him exposure to many different areas of science including, human physiology & diseases, molecular biology, genetics and bioinformatics & biostatistics. During Houtan’s doctoral training with Dr. Peter W. Laird at USC, he gained new insight and understanding of the epigenetic changes associated with Glioblastoma multiforme, a primary brain tumor. Not only did this work lay the foundation for Houtan’s scientific curiosity in the field of epigenetics (specifically DNA methylation), but also fulfilled an exciting collaborative experience. As a member of The Cancer Genome Atlas (TCGA), Houtan traveled and worked closely with a number of different scientists around the nation allowing him a unique opportunity to share and discuss research ideas with other TCGA members. During his post-doctoral work, Houtan was supervised under Dr. Coetzee who is well known for his expertise in molecular biology, specifically works with ChIP-Chip and epigenetics in the area of prostate cancer. Recently his involvement with Genome-wide association studies (GWAS) to characterize risk loci in prostate cancer has received a lot of attention around the world. In the ‘post-GWAS’ era, the aim is to understand the functional consequences underlying cancer risk loci. In doing so, novel biological insights may be revealed leading to clinical benefits, including the development of reliable biomarkers, effective screening and disease prevention strategies. GWAS have identified more than 50 genetic risk loci for prostate cancer, however exactly how they affect risk is unknown. In this project, Houtan determined such mechanisms, revealing novel genes and preventive risk strategies. This work was the first comprehensive look at the 50+ risk loci for prostate cancer and provided a vital link to further study the biology of the proposed regions with an emphasis on androgen receptor signaling. Houtan’s experience in Dr. Laird and Dr. Coetzee’s lab has enriched his skills and allowed him the opportunity to learn new areas of science. Currently, Houtan is an assistant professor at the University of Sao Paulo at the Ribeirao Preto Medical School in the department of genetics. Houtan’s goal as an assistant professor is to develop the bioinformatics courses and program and study the area of genomics and epigenomics in human cancer.

  • Michela Biancolella, Barbara K Fortini, Stephanie Tring, Sarah J. Plummer, Gustavo A. Mendoza-Fandino, Jaana Hartiala, Michael J. Hitchler, Chunli Yan, Fredrick R. Schumacher, David V. Conti, Christopher K. Edlund, Houtan Noushmehr, Simon G. Coetzee, Robert S. Bresalier, Dennis J. Ahnen, Elizabeth L. Barry, Benjamin P. Burman, Judd C. Rice, Gerhard A. Coetzee, Graham Casey: “Identification and Characterization of Functional Risk Variants for Colorectal Cancer Mapping to Chromosome 11q23.1” Oxford University Press published in 2013. View.
  • Cameron W. Brennan, Roel G.W. Verhaak, Aaron McKenna, Benito Campos, Houtan Noushmehr, et al.: “The Somatic Genomic Landscape of Glioblastoma” Cell 155 published October 2013. View.
  • The Cancer Genome Atlas Research Network, John N Weinstein, Eric A Collisson, Gordon B Mills, Kenna R Mills Shaw, Brad A Ozenberger, Kyle Ellrott, Ilya Shmulevich, Chris Sander & Joshua M Stuart: “The Cancer Genome Atlas Pan-Cancer analysis project” Nature Genetics 45:10 published October 2013. View.
  • Suhn Kyong Rhie, Simon G. Coetzee, Houtan Noushmehr, Chunli Yan, Jae Mun Kim, Christopher A. Haiman, Gerhard A. Coetzee: “Comprehensive Functional Annotation of Seventy-One Breast Cancer Risk Loci” PLoS ONE 8:5 published May 2013.
  • Paul D P Pharoah, et al: “GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer” Nature Genetics 45:4 published April 2013. View.
  • Jennifer Permuth-Wey, Kate Lawrenson, Howard C. Shen, et al: “Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31” Nature Communications 4:1627 published March 2013. View.

Elliot Rosen

Elliot Rosen is a candidate for a Master’s in Biotechnology at JHU. He currently studies chemotherapy and radiation-induced cardiotoxicity with the U.S. Food and Drug Administration. Mr. Rosen received his B.S. in Environmental Science and Policy from the University of Maryland in 2008.

  • Jennifer S. Dickey, Yanira Gonzalez, Baikuntha Aryal, Steven Mog, Asako J. Nakamura, Christophe E. Redon, Ulrich Baxa, Elliot Rosen, Gang Cheng, Jacek Zielonka, Palak Parekh, Karen P. Mason, Joy Joseph, Balaraman Kalyanaraman, William Bonner, Eugene Herman, Emily Shacter, V. Ashutosh Rao: “Mito-Tempol and Dexrazoxane Exhibit Cardioprotective and Chemotherapeutic Effects through Specific Protein Oxidation and Autophagy in a Syngeneic Breast Tumor Preclinical Model.” PLoS ONE 8(8) published in 2013. View.

Priyanka Shah

Priyanka Shah received her Bachelor’s degree in Biotechnology from Dr. D.Y. Patil Institute, Mumbai-India (2009). Soon afterward, additional strengthening of her fundamental Biology principals made Priyanka pursue a Master’s degree in Biotechnology with a concentration of Cancer Biology and Drug Discovery from Johns Hopkins University (2011). Priyanka’s job search led her to her current position at the National Institutes of Neurological Disorders and Stroke (NINDS) at NIH. Priyanka works in a Crystallography lab and is part of a team that is actively involved in seeking active state Neurotensin structure as close as it can get to native human protein form. Priyanka is also involved in a Career Development committee of NIH, as a part of which she organized bi-monthly panels on current Science-based career fields that are developing today. An avid reader and rock climber, Priyanka hopes to continue her pursuit of Science more from a Management point of view in the future.

  • Jim F. White, Nicholas Noinaj, Yoko Shibata, James Love, Brian Kloss, Feng Xu, Jelena Gvozdenovic-Jeremic, Priyanka Shah, Joseph Shiloach, Christopher G. Tate & Reinhard Grisshammer: “Structure of the agonist-bound neurotensin receptor” Nature 490 published in 2012. Download (PDF).

Maria Ximena Sosa

Maria Ximena Sosa graduated from Tufts University with a double major in Biology and Biotechnology. Soon after graduation, she joined the McKusick-Nathans Institute of Genetic Medicine (IGM) at The Johns Hopkins University School of Medicine to work with Dr. Aravinda Chakravarti to study the etiology of complex diseases, specifically Hirschsprung (HSCR), Autism, Hypertension and Sudden Cardiac Death. Her current project involves the manipulation of Zebrafish to model human disease by using reverse genetics to validate candidate genes for Hirschsprung and Autism. She has extensive hands-on experience in Next-Generation sequencing and microarrays. Maria graduated from the MS in Biotechnology Program in 2010. Maria’s goal is to work in the field of translational research and personalized medicine.

  • Maria Ximena Sosa, I. K. Ashok Sivakumar,Samantha Maragh, Vamsi Veeramachaneni, Ramesh Hariharan, Minothi Parulekar, Karin M. Fredrikson, Timothy T. Harkins, Jeffrey Lin, Andrew B. Feldman, Pramila Tata, Georg B. Ehret, Aravinda Chakravarti: “Next-Generation Sequencing of Human Mitochondrial Reference Genomes Uncovers High Heteroplasmy Frequency” PLoS Comput Biol 8(10) published October 2012. View.
  • Srirangan Sampath, Shambu Bhat, Simone Gupta, Ashley O’Connor, Maria Ximena Sosa, Andrew B. West, Dan E. Arking, Aravinda Chakravarti: “Defining the Contribution of CNTNAP2 to Autism Susceptibility”  PLoS ONE 8(10) published October 2013. View.

Sotirios Stergiopoulos

Dr. Sotirios StergiopoulosSotirios G. Stergiopoulos, MD, is a physician trained in Internal Medicine and Cancer genetics from the National Institutes of Health, Albert Einstein College of Medicine and Harvard Medical School. Sotirios has held various clinical academic faculty positions. He holds a current position as a Teaching Attending at Albert Einstein College of Medicine. Sotirios also is the Executive Medical Director and the Breast Cancer Lead at Celgene Corporation. He has held roles of increasing responsibility in medical affairs and clinical development at other companies such as Bayer Pharmaceuticals and Novartis Pharmaceuticals. Sotirios has been elected to the Sigma Xi Research Society as well as the prestigious New York Academy of Medicine and Royal Society of Medicine (UK). He has completed the requirements for the Master of Biotechnology Enterprise and Entrepreneurship program.

Interview with Dr. Sotirios Stergiopoulos

What was your background before coming to Johns Hopkins? Did you complete the program as a full-time or part-time student? My background coming in to the program was that I was a Global Brand Medical Director at Novartis working in Oncology as a therapeutic area in medical affairs. I was taking 2 classes a semester.

What were your career objectives and have they changed since pursuing your MBEE? My career objectives were to better understand the field I had entered. My concern was that as a physician with very little overall understanding of the Biotech/Pharma world, I was working in a silo and not understanding completely the field I had entered.

Why did you decide to pursue your MBEE? I was invited to a dinner where there was a business development discussion occurring. The conversation was stimulating as there were discussions about new compounds and how to develop them and the cost to acquire. While I found this absolutely interesting, I realized I knew so little about this aspect of the industry and had to get a better sense of it. I considered an MBA, but felt it was too broad and not focused as much on Biotech/Pharma. Therefore, when I found this program I was intrigued. I must say, that it was the BEST decision of my career.

How do you use your MBEE in your everyday work life? So many parts of what I have learned from the program are used daily. Whether it is calculating the valuation of a company or an asset, to how to manage certain people. Every day, I am grateful for the opportunity I had to learn so much of the pertinent topics that allow me to be able to excel in my career.

Would you do anything differently from your time at Hopkins? One area that I still feel I could learn more about is Intellectual property. This is such a big issue when creating new molecules and the information gained from the research. The biggest worries and challenges faced are who holds the intellectual property. A constant struggle between academia and industry as well as company vs company.

Are there any aspects from the program that stuck out to you as particularly helpful in relation to your success? Apart from certain knowledge gaps, such as Finance and marketing, the overall program instilled a more entrepreneurial component that I had not appreciated prior. My mindset was very science-oriented with no further view of the whole picture of drug development.

As SVP and Head of Global Medical Affairs at IPSEN, Chairman of the Board of a biotech startup, and President of the Board of Governors of the Accreditation Counsel for Medical Affairs, your career is already quite successful and diverse. What do you see for yourself and your career in the future? Recently, I have been named as the Chief Medical Officer (CMO) of Ipsen Biosciences. This is a great advancement in my career and affords me to make the difficult decisions for the Medical component of our industry. Eventually, I would like to become a CEO and be able to run a Biotech company as the General Director.

Did you have a favorite course or professor? I must say that one of my favorite courses, taught by Dr. Lynn Johnson Langer, was one on Technimanagement, the management of highly technical people. This is such a difficult challenge as you deal with people that are so advanced in their field but need management and guidance. Very tricky!

The majority of the MBEE program is online, how did that affect your experience with the program? The online component is a huge plus for people such as myself that had to travel for work continuously as well as the time to be at home with a young family (2 children under the age of 6) I guess the one downside would be the human interaction and being able to see your classmate’s reactions as well as your professors. Key component of learning is seeing reactions.

What is your advice to current or prospective MBEE students? Learn as much as you can, not for the grades but for the benefit of being able to advance in your career and truly be knowledgeable about what you are doing.

Selected Bibliography

  • Sotirios Stergiopoulos: “Emerging pathways in treating human epidermal growth factor receptor-2-negative breast cancer” New Horizons in Translational Medicine, 2015. Download (PDF).
  • Catherine Lombard-Bohas, MD, James C. Yao, MD, Timothy Hobday, MD, Eric Van Cutsem, MD, PhD, Edward M. Wolin, MD, shok Panneerselvam, PhD, Sotirios Stergiopoulos, MD, Manisha Shah, MD, Jaume Capdevila, MD, and Rodney Pommier, MD “Impact of Prior Chemotherapy Use on the Efficacy of Everolimus in Patients With Advanced Pancreatic Neuroendocrine Tumors” Pancreas, 2014. Download (PDF).
  • Daniel Y. Heng, James Signorovitch, Elyse Swallow, Nanxin Li, Yichen Zhong, Paige Qin, Daisy Y. Zhuo, Xufang Wang, Jinhee Park, Sotirios Stergiopoulos, Christian Kollmannsberger “Comparative Effectiveness of Second-Line Targeted Therapies for Metastatic Renal Cell Carcinoma: A Systematic Review and Meta-Analysis of Real-World Observational Studies” PLoS ONE 9(12). Download (PDF).

Andrew W. Tanner

Andrew Tanner received his bachelor’s degree in Biology from Montclair State University in May of 2007 before coming to Johns Hopkins. While attending JHU Andrew worked for Novartis Pharmaceuticals in the Microbiology division of QA.  Following his graduation in May of 2010 he decided to leave this job to pursue a Ph.D. in Microbiology and Molecular Genetics at the University of Medicine and Dentistry of New Jersey (Soon to be a part of Rutgers University on July 1st).  At present, in the lab of David Dubnau, Ph.D., he studies the modulation of a major transcription factor in Bacillus subtilis (Spo0A) which is responsible for determining whether a given cell chooses to swim, attach to a surface, form a spore or take up extracellular DNA. Read about his recent publication here:

  • Carabetta, V. J., A. W. Tanner, T.M. Greco, M. Defrancesco, I.M. Cristea, and D. Dubnau (2013). “A complex of YlbF, YmcA and YaaT regulates sporulation, competence and biofilm formation by accelerating the phosphorylation of Spo0A.” Molecular microbiology 88(2): 283-300. View.

Iosif Vardinogiannis

Iosif Vardinogiannis is a recent graduate from Boston University (May 2013) with a degree in Biology. As a senior at BU, Iosif performed and assisted in the research of Dr. Thomas Gilmore in BU. Dr. Gilmore’s research involved experiments on Diffused Large B-cell Lymphoma cell lines in response to Histone Deacetylase inhibitors as well as studying the Rel/Nf-κB family of transcription factors. Iosif is currently enrolled in the MS in Biotechnology, with a concentration in Biotechnology Enterprise.

  • Ryan C. Thompson, Iosif Vardinogiannis and Thomas D. Gilmore: “Identification of an NF-κB p50/p65-responsive site in the human MIR155HG promoter” BMC Molecular Biology 14:24 published in 2013. Download (PDF).
  • Ryan C. Thompson, Iosif Vardinogiannis and Thomas D. Gilmore: “The Sensitivity of Diffuse Large B-Cell Lymphoma Cell Lines to Histone Deacetylase Inhibitor-Induced Apoptosis Is Modulated by BCL-2 Family Protein Activity” PLOS ONE 8:5 published May 2013. Download (PDF).

Alex Zhavoronkov

Alex Zhavoronkov, Ph.D., is the director and a trustee of the Biogerontology Research Foundation, a UK-based think tank supporting aging research worldwide and is the founder of the International Aging Research Portfolio, a curated knowledge management system for aging research. He heads the laboratory of regenerative medicine at the Clinical Research Center for Pediatric Hematology, Oncology and Immunology and is the head of research at NeuroG and the co-founder of the First Oncology Research and Advisory Center and the First Open Institute for Regenerative Medicine for Young Scientists. Dr. Zhavoronkov is the author of “The Ageless Generation: How Advances in Biomedicine Will Transform the Global Economy”(Palgrave Macmillan, NY, 2013). He holds two bachelor degrees from Queen’s University, a masters in biotechnology from Johns Hopkins Universtity and a PhD in physics and mathematics from the Moscow State University. Read about his recent publications here:

  • Alex Zhavoronkov, Nawazish Mirza, Irog Artuhov, Edouard Debonneuil. “Evaluating the impact of recent advances in biomedical sciences and the possible mortality decreases on the future of health care and Social Security in the United States” Pensions 2012 Dec 14. 17, 241 – 251. doi: 10.1057/pm.2012.28. View.
  • Anastasia A. Zabolotneva, Alex Zhavoronkov, Andrew V. Garazha, Sergey A. Roumiantsev and Anton A. Buzdin. “Characteristic patterns of microRNA expression in human bladder cancer” Gene. doi: 10.3389/fgene.2012.00310. View.
  • Moskalev A, Plyusnina E, Shaposhnikov M, Shilova L, Kazachenok A, Zhavoronkov A. “The role of D-GADD45 in oxidative, thermal and genotoxic stress resistance” Cell Cycle. 2012 Oct 24;11(22). View Online. Zhavoronkov A, Smit-McBride Z, Guinan KJ, Litovchenko M, Moskalev A. “Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases.” J Mol Med (Berl). 2012 Oct 23. View.
  • Nepomnyashchaya Y.N., Artemov A.V., Roumiantsev S.A., Roumyantsev A.G., Zhavoronkov A. “Non-invasive prenatal diagnostics of aneuploidy using next-generation DNA sequencing technologies, and clinical considerations.” Clin Chem Lab Med. 2012 Sep 29;0(0):1-14. doi: 10.1515/cclm-2012-0281.
  • Moskalev A.A., Smit-McBride Z., Shaposhnikov M.V., Plyusnina E.N., Zhavoronkov A., Budovsky A., Tacutu R., Fraifeld V.E. “Gadd45 proteins: relevance to aging, longevity and age-related pathologies” Ageing Res Rev. 2012 Jan;11(1):51-66. doi: 10.1016/j.arr.2011.09.003
  • Zhavoronkov A, Cantor CR. “Methods for structuring scientific knowledge from many areas related to aging research” PLoS One. 2011;6(7):e22597. doi: 10.1371/journal.pone.0022597. View.
  • Bobrov P, Frolov A, Cantor C, Fedulova I, Bakhnyan M, Zhavoronkov A. “Brain-computer interface based on generation of visual images” PLoS One. 2011;6(6):e20674. doi: 10.1371/journal.pone.0020674. View.
  • V. A. Tverdislov, L. V. Yakovenko, A. A. Zhavoronkov. “Chirality as a problem of biochemical physics” Russian Journal of General Chemistry, November 2007, Volume 77, Issue 11, pp 1994-2005. View (PDF).
  • Dating AI: A Guide to Falling In Love with Artificial Intelligence Alex Zhavoronkoff, Ph.D. Re/Search Publications, San Francisco, 2012, ISBN: 978-1889307350
  • The Ageless Generation: How Advances in Biomedicine Will Transform the Global Economy Alex Zhavoronkov, Ph.D. Palgrave Macmillan, New York, 2013, ISBN: 978-0230342200

Catherine Campbell (Faculty Member)

Dr. Campbell has over 15 years of professional experience in bioinformatics and over a decade of experience in teaching bioinformatics. She also has substantial experience in bench research in molecular and microbiology. Dr. Campbell received her B.S. in Microbiology from Cornell University and her M.S. and Ph.D. from the University of Miami. During her career she has focused on the analysis of population based experiments designed to study both human disease and animal models of disease. Recent projects have involved designing informatics systems for government biodefense applications and in silico identification of medical countermeasures and pathogen identification in several types of pathogenic viruses. Past projects have included directing the development of informatics tools, developing institution wide training programs and participating in collaborative research and customized data analysis with both clinical and basic science investigators, researching a wide variety of complex neurological disorders. Her research work has encompassed both laboratory experiments and statistical and bioinformatics analysis of several important diseases including biodefense agents, Gaucher’s disease, multiple sclerosis, chronic fatigue syndrome, and neurofibromatosis. Dr. Campbell has been teaching bioinformatics for the JHU AAP program since 2006.

  • Amaya M., A. Baer, K. Voss, C. Campbell, C. Mueller, C. Bailey, K. Kehn-Hall, E. Petricoin III, A. Narayanan. “Proteomic strategies for discovery of novel diagnostic and therapeutic targets for infectious diseases.” Pathog. Dis. 7(2):175-187 2014. View.

Lawrence A. Husick (Faculty Member)

Lawrence A. Husick’s extensive experience as a technology consultant, computer system designer, and software author, as well as his career as an intellectual property lawyer give him a unique perspective on the need to focus on innovation as a central pedagogical theme. As a co-director of the FPRI Wachman Center Program on Teaching Innovation, he applies his background in both law and technology to the study of innovation as an organizing principle of history, science and technology, economics, and sociology. Mr. Husick holds a Bachelor of Science degree cum laude in Environmental Chemistry from Muhlenberg College in Allentown, Pennsylvania. He holds a Juris Doctor degree from the Washington College of Law in Washington, D.C., where he also did graduate work in microprocessor systems design.

Eric Langer (Faculty Member)

Eric Langer has over 20 years experience in biotechnology and life sciences international marketing, management, market assessment, and publishing. He has held senior management and marketing positions at biopharmaceutical supply companies. He is an experienced biotechnology strategist, marketing practitioner, publisher, and researcher. He has published, edited and authored numerous books, reports, and major studies on topics including: Advances in Biopharmaceutical Technology in China, Advances in Large-scale Biopharmaceutical Manufacturing, Biopharmaceuticals in the US Market, cell culture reports, media, sera, tissue engineering, stem cells, diagnostic products, blood products, genetics, DNA/PCR purification, blood components, and many others. He lectures extensively on pricing and channel management topics, and teaches at Johns Hopkins University and American University: Biotechnology Marketing, Marketing Management, Services Marketing, Advertising Strategy, and Bioscience Communication. He has developed numerous courses, classes and seminar programs, including Marketing in a Regulated Environment, Marketing Technical Products, and TechniManagement.™ In 1989 he co-founded BioPlan Associates, Inc. a biotechnology and life sciences marketing company that provides information, market research, pricing, and market analysis to biotechnology and healthcare organizations. He has launched and managed marketing programs for product lines ranging from $500k to $500 million. His company works with both large and small clients at commercial biotechs, non-profit organizations, and governments in assessing and evaluating markets, and marketing strategies and tactics.

  • Click here for a list of Eric’s publications.

Joshua Orvis (Faculty Member)

In addition to teaching courses at JHU, Joshua is a “Senior Bioinformatics Software Engineer” at the Institute for Genome Sciences in Baltimore as well as a consultant for the Broad Institute. Joshua’s undergraduate degree was in Microbiology and his graduate work was focused on Bioinformatics. He very much enjoys teaching and has taught graduate-level classes for most of the last 10 years. Joshua’s research projects tend to focus on single-genome annotation (eukaryotic and prokaryotic), metagenomics and transcriptomics. These have required a focus on distributed grid computing to manage the computational needs of large datasets, though he tries to stay as close to the biology as he can and not get distracted by technical fun.

Mathumathi Rajavel (Faculty Member)

Mathumathi Rajavel received her Master’s in Microbiology and Ph.D in Molecular Biology from Madurai Kamaraj University, India. Her Ph.D thesis was on understanding genetic instability in Streptomyces upon antibiotic exposure. Her postdoctoral training at Temple University was in Protein chemistry and then at Johns Hopkins University Bloomberg School of Public Health, she used molecular and biochemical approaches to understand the Cell Integrity Signaling. She is teaching for AAP Program since 2001 (core and elective courses) both online and onsite. She is currently an Assistant Professor at Morgan State University and her research involves manipulating bacteriophages to combat infections caused by multi-drug resistant bacterial pathogens.

  • Fouts DE, Klumpp J, Bishop-Lilly KA, Rajavel M, Willner KM, Butani A, Henry M, Biswas B, Li M, Albert MJ, Loessner MJ, Calendar R, Sozhamannan S. (2013). Whole genome sequencing and comparative genomic analyses of two Vibrio cholerae O139 Bengal-specific Podoviruses to other N4-like phages reveal extensive genetic diversity. Virol J. 28; 10: 165. View.

JHU Master’s Candidates in Biotechnology

“From the Bench to the Boardroom: Planning for Personalized Medicine,” Managing Innovations Class Book, published in 2012. This book is the product of the Fall 2012 Managing Innovation in the Life Sciences class taught at the Zanvyl-Krieger School of Arts and Sciences of the Johns Hopkins University. Each chapter author is a candidate for a Master’s Degree in the Advanced Biotechnology Program. Like others before it, this book is a class project, intended to address a lay audience about a topic of central importance in the life sciences: innovation and how the innovation process and innovators may be managed to best achieve value.